Arizona Cardinals vs San Francisco 49ers Odds & Lines
Best available NFL odds for Arizona Cardinals at San Francisco 49ers, Sun, 27 Sep 2026 20:05:00 GMT.
| Team | Moneyline | Spread |
|---|---|---|
| Arizona Cardinals | +470 | +11.5 (-110) |
| San Francisco 49ers | -600 | -11 (-115) |
Total (O/U): +47.5 — Over -115 / Under -115 (williamhill_us)
Odds shown are the best available across sportsbooks and update in real time. Get alerts on line movement and sharp money with the Bettor Alerts app.