New England Patriots vs Buffalo Bills Odds & Lines
Best available NFL odds for New England Patriots at Buffalo Bills, Sun, 04 Oct 2026 17:00:00 GMT.
| Team | Moneyline | Spread |
|---|---|---|
| New England Patriots | +160 | +4 (-115) |
| Buffalo Bills | -162 | -3 (-110) |
Total (O/U): +50.5 — Over -115 / Under -115 (williamhill_us)
Odds shown are the best available across sportsbooks and update in real time. Get alerts on line movement and sharp money with the Bettor Alerts app.